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Catalog# Product Description |
CN0205 IRF4 is a transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. |
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Species
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Rabbit
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Formulation
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250 µg/mL in 0.1 N Tris-acetate, pH7.0, 0.01% NaN3, and 50% glycerol
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Storage & Stability
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Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if properly stored.
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Immunogen
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Human IRF4 peptide-KLH conjugates
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Purification
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The antibody was affinity purified with Human IRF4 peptide on Agarose.
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Applications
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ELISA,WB, IP.
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Specificity
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The antibody recognizes IRF4 at around 50 kd.
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Scientific Description
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IRF4 also called lymphocyte-specific interferon regulatory factor. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
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Product Specific References
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1. Biochem. J. 1989. 257: 535-540.
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